In this article, we consider effects of PRP injection for treatment of female sexual dysfunction.
Currently accepted treatment for female sexual dysfunction are done. Generally, there are 4 classes of sexual dysfunction: hyposexual desire disorder, arousal disorder, orgasmic disorder and dyspareunia.
As one possible strategy, various materials have been injected in the periurethral area to treat sexual dysfunction and urinary incontinence. For example, calcium hydroxyapatite crystals for periurethral injection in the treatment of urinary incontinence. There is risk of discrete constriction that can associated with urinary obstruction, erosion, infection and granuloma formation which treat by surgical removal.
Injection of hyaluronic acid fillers has been used as a treatment to enhance orgasmic intensity by amplification of a controversial anatomical area in the anterior vaginal wall. But due to incidence of granuloma formation by hyaluronic acid fillers at the injection site, this therapy has been condemned.
In contrast to the above mentioned synthetic materials, platelet rich plasma (PRP) has been demonstrated to be effective and with minimal risks and side effects. PRP activates stem cells and areas of injection, resulting in rejuvenation and even enhancement of damaged or undamaged tissues. This injection flows into tissues as a non- viscous liquid.
Those women who suffers from dyspareunia or other sexual dysfunctions, PRP is injected into their periurethral and clitoris. First, a topical anesthesia cream was applied to the anterior vaginal wall. The clitoral hood was retracted and cream applied to the clitoris. Delaying the PRP injection for 20 minutes after anesthetic application. After isolation of the PRP, calcium chloride was added to the 5ml of PRP isolate to activate the thrombin, and causing degranulation of platelets, releasing growth factors and cytokines.
Results show that some cases of female sexual dysfunction, manifested by decreases in sexual desire, arousal, lubrication and orgasmic responsiveness, may be treated with specifically directed injection of PRP.
PRP injection induces growth of new tissue by activation of stem cells that are indigenous to most parts of the body. PRP is activated and injected into the vagina and clitoris, growth factors and cytokines may cause differentiation of steam cells in fibroblast growth, and results in improving physiologic responsiveness, and neuronal regrowth in the vagina and clitoral area, and then, sensitivity and blood flow will be increased in these areas.
PRP injection is an effective method to treat certain types of female sexual dysfunction, specially in the areas of desire, arousal, lubrication and orgasm. Improvement in satisfaction and pain were noted.
Contact Dr. Mitra Bahmanpour, Gynecologist
Address: Khalij Fars Building. Next to 18th st. Velenjak. Tehran. Iran
Tell: +9821- 26641827